Sigma

Cholic acid

C1129 -

from ox or sheep bile, ≥98%

DOWNLOAD MSDS (PDF)

Synonym: 3α,7α,12α-Trihydroxy-5β-cholanic acid, Cholanic acid

  • CAS Number: 81-25-4

  • Empirical Formula (Hill Notation): C24H40O5

  • Molecular Weight: 408.57

  • Beilstein Registry Number: 2822009

  • EC Number: 201-337-8

  • MDL number: MFCD00003672

  • PubChem Substance ID: 24892356

Description

Application

Non-denaturing ionic detergent used for extraction of membrane proteins.

Biochem/physiol Actions

Bile Acid

Other Notes

Tandem MS data independently generated by Scripps Center for Metabolomics is available to view or download in PDF format on the Safety and Documentation tab. Tested metabolites are featured on Scripps Center for Metabolomics: METLIN Metabolite Database.

Packaging

1 kg in poly btl

25, 100, 500 g in poly btl

Price and Availability

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Documents

Certificate of Analysis

Certificate of Origin

FT-IR Raman
FT-NMR
Gene Information
Structure Search
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Safety Information

Personal Protective EquipmentEyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
WGK Germany2
RTECSFZ9350000
Technical information & documentation associated with this product is available in the Safety & Documentation tab.

Articles

Bile Acids

The liver excretes excess cholesterol in the form of bile acids. Bile acids serve two purposes: to remove unwanted cholesterol from the body and to aid in lipid digestion in the intestine. Bile acids...
BioFiles 2007, 2.7, 17.
Keywords: Absorption, Digestions, PAGE, Transcription

References

Lazarou, M., et al., Assembly Of Nuclear DNA-encoded Subunits Into Mitochondrial Complex IV, And Their Preferential Integration Into Supercomplex Forms In Patient Mitochondria. FASEB J. 276, 6701-13, (2009)

Flanagan, R.C., et al., Examination Of Campylobacter Jejuni Putative Adhesins Leads To The Identification Of A New Protein, Designated FlpA, Required For Chicken Colonization. Infect. Immun. 77, 2399-407, (2009) Abstract

Escobar-Alvarez, S., et al., Inhibition Of Human Peptide Deformylase Disrupts Mitochondrial Function. Mol. Cell. Biol. 30, 5099-109, (2010) Abstract

Siggs, O.M., et al., X-linked Cholestasis In Mouse Due To Mutations Of The P4-ATPase ATP11C. Proc. Natl. Acad. Sci. U. S. A. 108, 7890-5, (2011) Abstract

Merck 14,2203

Beil. 10,IV,2072

FT-IR 2 (3), 4240:B / FT-IR 1 (2), 1057:C / FT-NMR 1 (3), 594:B / IR-Spectra (3), 1499:G / IR-Spectra (2), 1282:C / NMR-Reference 2 (2), 929:A / RegBook 1 (2), 2867:M / Sax 6, 788 / Sigma FT-IR 1 (1), 1221:D / Structure Index 1, 459:A:6


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